MilfordMD Cosmetic Dermatology Surgery & Laser Center is Among the First to Offer Newly Approved Fillers, Restylane Refyne and Defyne to Treat Laugh Lines
Galderma announced in December 2016 that the FDA had approved its cosmetic hyaluronic acid fillers Restylane Refyne and Restylane Defyne for treatment of laugh lines, or nasolabial folds. MilfordMD Cosmetic Dermatology Surgery & Laser Center, in Milford, Penn., is among the first practices nationally offering the newly approved fillers.
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MilfordMD Cosmetic Dermatology Surgery & Laser Center is among the first practices to offer newly FDA-approved Restylane Refyne & Restylane Defyne for the treatment of laugh lines (nasolabial folds).
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“Scientific advances in hyaluronic acid and other filler products in the last few years is one of the most exciting trends in cosmetic surgery,” says cosmetic surgeon Dr. Richard Buckley, Medical Director of MilfordMD Cosmetic Dermatology Surgery & Laser Center. “These newest fillers in our toolbox of cosmetic solutions, Refyne and Defyne, are targeted to treat moderate to severe facial wrinkles and folds, as well as deep facial wrinkles and folds on the face.”
Called next-generation flexible hyaluronic acid dermal fillers, Refyne and Defyne are manufactured with XpresHAn Technology, according to Galderma, the company that makes Restylane filler products. “The laugh lines are a dynamic area of the face, with a lot of constant movement. These fillers are flexible to accommodate that movement, while offering a lasting effect. Refyne and Defyne have been shown in studies to last up to a year,” Dr. Buckley says.
The XpresHAn Technology manufacturing process results in a smooth injectable gel that offers natural looking results. The advanced technology customizes the degree of hyaluronic acid (HA) crosslinking in each filler, which allows providers the flexibility to meet different patient’s cosmetic needs.
“The increased flexibility of Restylane Refyne provides subtle support,” Dr. Buckley says. “Defyne, on the other hand, is a more supportive filler with less flexibility. The filler choice would depend on the depth and extent of the wrinkles or lines.”
Galderma released news on two phase 3 studies on Refyne and Defyne, which looked at the individual filler’s safety and effectiveness. One study involved 171 patients; the other 162 patients. Both studies found that the majority of patients who received filler treatment had noticeable improvement in the severity of their wrinkles and the improvement lasted up to 12 months.
Researchers used a five-point rating to determine the fillers’ effects on wrinkle severity, with a grade of one being the absence of wrinkles and grade five being extremely deep and long wrinkles. According to the studies, 79 percent of Restylane Refyne patients and 77 percent of Restylane Defyne subjects had at least a one-grade improvement on the scale after six weeks.
Much like the post-treatment side effects reported with other Restylane fillers, the most common post-injection findings were mild to moderate redness, swelling, bruising, lump or bump formation and pain or tenderness at the injection site that lasted one to two weeks.
“These fillers have a good safety profile. They are new to the U.S. market, but both were approved in Europe in 2010 and more than one million patients have been treated using these fillers worldwide,” Dr. Buckley says. “In fact, the entire portfolio of Restylane fillers has been keeping our patients looking their best for many years. These include fillers to diminish wrinkles, create fuller lips, add volume to the cheeks and to restore the triangle of youth.”
About MilfordMD Cosmetic Dermatology Surgery & Laser Center:
The MilfordMD Cosmetic Dermatology Surgery & Laser Center offers state-of-the-art highly specialized procedures in laser and cosmetic-surgery and aesthetic skin care. In addition to its AAAHC accredited surgical center and extensive laser surgery capabilities, MilfordMD offers physician designed skin care products for home use. Milford Pennsylvania’s MilfordMD Cosmetic Dermatology Surgery & Laser Center is sought out by patients from around the world for expertise and innovation in cosmetic treatments performed by Richard E. Buckley, M.D. and Marina Buckley, M.D.
MilfordMD Cosmetic Dermatology Surgery & Laser Center is located at 303 W. Harford Street, Milford, PA 18337. Tel: (800) 664-1528. For real patient video testimonials, visit our MilfordMD YouTube channel.
