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Restylane® / Perlane®


Restylane® or Perlane® are FDA-approved cosmetic dermal fillers that replace lost volume and restore youthful contours to the skin to smooth away moderate to severe facial wrinkles and folds1, such as the lines from your nose to the corners of your mouth (nasolabial folds). Restylane is the world’s most used, most studied dermal filler, and has been used in over 70 countries and in more than 1.4 million treatments in the U.S.

If you’re considering treatment for your facial wrinkles and folds, we invite you to learn important facts about Restylane® and Perlane®, including how they provide structural support and lift to nasolabial folds. In this section, you’ll learn where Restylane® or Perlane® can be used and see examples of how either treatment can help you reach your goal of a more youthful appearance. The procedure is non-surgical, and its effects are virtually instantaneous, with long-lasting for about six to eight months2.

Restylane® and Perlane® are made of hyaluronic acid is produced by a biotechnical process and contain no animal proteins. In the human body, natural hyaluronic acid provides volume and fullness to the skin. The hyaluronic acid in Restylane® and Perlane® has been modified slightly to last longer than the body’s hyaluronic acid. Restylane and Perlane are hydrophilic or “water loving.” The hydrophilic nature of these hyaluronic acid molecules and their three dimensional structure allows them to bind many times their own weight in water. As hyaluronic acid begins to degrade, each molecule binds to more water which helps to maintain its volume for about six months. This limits any risk of animal-based disease transmission or allergic reactions. Restylane and Perlane contain trace amounts of gram-positive bacterial proteins and are contraindicated for patients with a history of allergies to such material. No allergy testing is required before use.

(View the befores and afters of Restylane treatments)



MilfordMD Cometic Dermatology Surgery & Laser Center